A Pilot Study of the Use of Picrorhiza kurroa in Patients with Malaria

Background and Purpose: Malaria is potentially a severe disease caused by infection of red blood cells with protozoan parasites the genus Plasmodium. an important cause death, illness in children pregnant women, especially Africa The present study aimed to develop alternative treatment that at may be effective safe against falciparum & vivax malaria easily available locally culturally acceptable. To confirms claims traditional herbal medicinal plants Picrorhiza kurroa was analyzed using water alcoholic extracts.
 Methods: conducted on 45 subjects, 24 aqueous extract 21 alcohol assess clinical efficacy plant Plasmodium P. Dera Ismail Khan. roots were extracted Soxhlet extractor triple distilled ethanol as solvent obtain both extracts kurroa. Both are formulated capsule 500 mg.
 Results: determined clinically pathologically patients from 14 50 years sexes, two capsules mg stat followed one twice daily for three days consecutively given. After 44.44% recovered, among them 85% (17/45) male 15% (3/45) female. drug considered further research same plant.
 Conclusion: concluded qualified active compound undergo investigation its antimalarial activity constituents should investigated better outcomes field medicines.